Read e-book online Analysis of Complex Diseases: A Mathematical Perspective PDF

By Guanyu Wang PhD

A advanced disorder contains many etiological and possibility components working at a number of levels—molecular, mobile, organismal, and environmental. The occurrence of such ailments as melanoma, weight problems, and diabetes are expanding in prevalence, urging us to imagine essentially and use a broader viewpoint to spot their connection and revolutionize remedies. the certainty of organic information derived from learning ailments could be better by way of theories and mathematical types, which make clear the massive photo and support to bare the overarching mechanisms that govern complicated organic phenomena.

Focusing on illnesses relating to mobile power metabolism, equivalent to melanoma and diabetes, Analysis of advanced ailments: A Mathematical Perspective provides a holistic process for illuminating the molecular mechanisms of those illnesses and the evolutionary underpinning in their simultaneous epidemics. utilizing arithmetic to spot styles of deviation from normality, or the fit state—spanning a number of degrees from molecules to the organism—the writer identifies a number of dynamical behaviors that correspond to both mobile body structure or pathology. He makes use of the data from a number of degrees in an effort to improve a unified conception, including the invention that yes ailments may well stem from well-evolved, important mechanisms activated within the improper context.

This ebook is split into 3 elements. half I specializes in the organismal point to explain basic body structure and the way the physique as an entire meets its sensible requisites. half II addresses the subcellular, molecular point to clarify the organizing ideas of mobile biomolecules to fulfill the calls for of the organism. half III examines advanced illnesses by means of combining details from the organismal point and the molecular point, delivering a paradigm that may be prolonged to the examine of alternative different types of illnesses.

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Analysis of Complex Diseases: A Mathematical Perspective by Guanyu Wang PhD


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